Sugarreset Side Effects and Who Should Check With a Doctor
The most likely Sugarreset side effects are jitters or poor sleep from caffeine, and stomach upset from xylitol.
Gymnema, chromium and ginseng may add to diabetes drugs, and grapefruit and a licorice compound can affect some drugs and blood pressure. Ask your doctor first if you take any medication.
To see if it suits you, read who it is for.
What side effects can Sugarreset cause?
A quick map first. The sections below explain each one.
Most people who react to Sugarreset would likely notice mild effects: a jittery feeling, poor sleep or an upset stomach. The rarer risks come from how some herbs act with medicines, the liver and blood pressure.
No safety study has tested this exact formula. So this page works from the label and from what research says about each ingredient. The amounts inside the 200 mg blend are not published, which makes each risk hard to size.
Possible Sugarreset side effects and the ingredients linked to them
| Possible effect | Likely source in the blend | How common |
|---|---|---|
| Jitters, fast heartbeat, poor sleep | Guarana, green tea (caffeine); Panax ginseng | Most likely, if you are caffeine-sensitive |
| Gas, bloating, loose stools | Xylitol (sweetener) | Possible, rises with dose |
| Low blood sugar with diabetes drugs | Gymnema, chromium, ginseng | Possible when combined with medicine |
| Changes in how some drugs work | Grapefruit extract | Depends on the drug |
| Higher blood pressure, low potassium | Monoammonium glycyrrhizinate (licorice); eleuthero | Mainly with large amounts |
| Liver injury | Gymnema, green tea extract | Rare |
How much caffeine is in Sugarreset drops?
Two blend ingredients carry caffeine. The label gives no number.
The label does not say. Guarana seed and green tea leaf are both natural sources of caffeine, and both sit inside the 200 mg blend. So the caffeine per 1 mL is under 200 mg and is likely far less. The exact figure is not published.
The FDA says up to 400 mg of caffeine a day is not generally linked to harmful effects in healthy adults (FDA, Caffeine). People differ a lot, though. Some feel shaky after one cup of coffee.
- Take the drops in the morning, as the label suggests
- Count them as one more caffeine source next to coffee, tea, soda and energy drinks
- Stop or cut to 1 dropper if you notice a racing heart, shakiness or poor sleep
Ginseng can also cause trouble sleeping; NCCIH lists insomnia as its most common side effect (NCCIH, Asian ginseng). Our caffeine in supplement blends article covers hidden caffeine in more depth.
Can Sugarreset cause low blood sugar with diabetes medicines?
The biggest safety question for anyone on diabetes treatment.
It could, in people who take diabetes medicines. Gymnema lowered glucose in small studies of people with type 2 diabetes. Chromium and ginseng may also add to the effect of these drugs. Combined with insulin or a sulfonylurea, the total effect could push blood sugar too low.
NCCIH warns that some supplements may interact with diabetes medicines and that none should replace proven care (NCCIH, Diabetes and supplements). Sugarreset is not a diabetes treatment. Talk to your doctor before you start, and never change a diabetes medicine because of a supplement.
Our supplements and diabetes medicines guide lists questions to take to your doctor.
Sugarreset and the liver: gymnema and green tea
Liver injury is rare, but two blend ingredients have been linked to it. LiverTox lists gymnema as a possible rare cause of liver injury (LiverTox, Gymnema). Concentrated green tea extract has also been tied to rare liver damage in supplement users (NIH ODS, Weight-loss supplements).
The amounts in these drops are likely small. Still, anyone with liver disease, or who drinks heavily, should ask a doctor before starting.
Can Sugarreset interact with other medicines?
Several blend ingredients can change how medicines work.
Sugarreset blend ingredients with known drug interactions
| Ingredient | What it can do | Medicines to ask about |
|---|---|---|
| Grapefruit extract | Grapefruit can change how some drugs are broken down (FDA, Grapefruit and drugs). | Some statins, blood pressure drugs, anti-anxiety drugs, transplant drugs |
| Chromium | May add to diabetes drugs and reduce thyroid medicine absorption (NIH ODS, Chromium). | Insulin, metformin, levothyroxine |
| Astragalus | May interact with drugs that affect the immune system (NCCIH, Astragalus). | Transplant drugs, other immune suppressants |
| Eleuthero | May raise blood pressure, blood sugar and bleeding risk (LactMed, Eleuthero). | Blood thinners, blood pressure and diabetes drugs |
| Licorice compound | Large amounts of glycyrrhizin can raise blood pressure and lower potassium (NCCIH, Licorice root). | Water pills, heart drugs such as digoxin, blood pressure drugs |
| Guarana, green tea | Caffeine adds to other stimulants. | Stimulant drugs, decongestants, some asthma drugs |
A pharmacist can check your full medicine list against the label in a few minutes. Bring the bottle, or a photo of the Supplement Facts panel.
Sugarreset, blood pressure and the heart: licorice and L-arginine
The blend lists monoammonium glycyrrhizinate, a compound from licorice root. In large amounts, glycyrrhizin can raise blood pressure and lower potassium. The amount in Sugarreset is not published. People with high blood pressure, heart disease or kidney disease should ask a doctor first.
L-arginine is also in the blend. In the VINTAGE MI trial, people who had just had a heart attack took up to 3 g of L-arginine three times a day. It did not help, and the trial stopped early after deaths in the arginine group (Schulman et al., 2006 (VINTAGE MI)).
Some context helps here. That trial used about 9 g a day. An even share of this blend is about 9 mg per mL, roughly a thousand times less. Even so, anyone who has had a heart attack should clear any arginine supplement with a cardiologist.
Can Sugarreset upset your stomach? Xylitol and pets
The sweetener is gentle for most people and toxic for dogs.
Xylitol is a sugar alcohol used to sweeten the drops. Sugar alcohols can cause gas, bloating and loose stools, and symptoms rise with the dose (Lenhart & Chey, 2017). One or two droppers likely hold a small amount, but people with IBS may notice it more.
Xylitol is much more dangerous for dogs. Even small amounts can cause a sudden drop in a dog's blood sugar and liver failure. Keep the bottle closed and out of reach. If a dog gets into it, call a vet at once.
- Start with 1 dropper for the first week if your stomach is sensitive
- Count other sugar-free gum, mints and sweets toward your xylitol total
- Stop if loose stools last more than a couple of days
Who should not take Sugarreset without a doctor's approval?
The label's caution: “Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.”
Pregnant or nursing
The label asks you to consult a physician. LactMed finds no good human evidence for eleuthero and no safety data in nursing (LactMed, Eleuthero).
Under 18
The label says children under 18 should consult a physician. This site sells the drops for adults only.
Anyone on diabetes medicine
Gymnema, chromium and ginseng could add to your medicine. Your doctor decides, and your medicine stays as prescribed.
Heart, liver or kidney disease
Licorice, caffeine, L-arginine, gymnema and green tea each raise questions here.
Surgery coming up
Eleuthero may raise bleeding risk. Tell your surgeon about every supplement you take.
Caffeine-sensitive
The caffeine amount is not published. Start low and take it in the morning.
When to stop Sugarreset and call a doctor
Clear rules for when a side effect needs attention.
Stop right away
Stop the drops if you notice any sign of low blood sugar, liver trouble, chest pain, a racing heart, swelling of the face or trouble breathing.
Get help fast when it is serious
Call 911 for chest pain, trouble breathing, confusion or fainting. Take the bottle with you.
Call your doctor for milder effects
Poor sleep, stomach upset or higher blood pressure readings are worth a call, even if they fade.
Tell the order desk
Call the order desk with your order ID and lot number. It helps trace the batch and can start a refund within 60 days.
How to take the drops safely: how to use Sugarreset. What is in each serving: Sugarreset ingredients.
Sugarreset side effects questions
What are the most common Sugarreset side effects?
The most likely ones are a jittery feeling or poor sleep from the caffeine sources, and gas or loose stools from xylitol. Both tend to be mild. Stop the drops if they bother you.
Can Sugarreset keep me awake?
It might. The blend holds guarana and green tea, which contain caffeine, and ginseng can also disturb sleep. Take the drops in the morning, as the label suggests, and cut back on coffee if you notice a change.
Can I take Sugarreset if I use insulin or metformin?
Only after you talk to your doctor. Gymnema, chromium and ginseng may add to the effect of diabetes medicines. Never change your medicine dose because of a supplement.
Is Sugarreset bad for the liver?
Liver injury is rare, but gymnema and concentrated green tea extract have both been linked to it. Stop the drops and call a doctor if you notice dark urine, yellow eyes or pain under the right ribs.
Does Sugarreset raise blood pressure?
It may for some people. The blend holds a licorice compound, caffeine sources and eleuthero, which can each nudge blood pressure. The amounts are not published, so check your readings if you have high blood pressure.
Can I take Sugarreset before surgery?
Tell your surgeon you take it. Eleuthero may raise bleeding risk, and several herbs can affect blood sugar and blood pressure. Many surgeons ask patients to pause supplements for a while before an operation.
What should I do if my dog drinks Sugarreset?
Call a vet or a pet poison line right away. The drops contain xylitol, which can cause a sudden drop in blood sugar and liver damage in dogs. Do not wait for symptoms.
Ready to try Sugarreset?
Order from the U.S. authorized merchant, keep your order email, and you are covered by the 60-day money-back guarantee. Questions before you buy? The Sugarreset contact page lists every desk.
Keep reading
Supplements & diabetes meds
Ingredients to discuss, low blood sugar signs, doctor questions and an honest 10-point score.
Read more →Ingredients
All 23 active ingredients, the 200 mg blend math, research doses and the liquid base.
Read more →How to use
Label directions, dropper size, timing, taste, storage and medicine checks.
Read more →
